2. Introduction
Most commonly occurring connective tissue
fibers.
Most abundant protein in mammals (25-35% of
all proteins)
Made up of collagen protein (Type I fibrils)
These fibers are flexible but inelastic.
Their diameter is 2-10 μm.
Found in Cartilage, Bone, Tendon and
Ligament
3. Structure
In LM, it appears interwoven running
randomly in all directions.
When not under stress, they show wavy
pattern
In EM, it shows collagen fiber is further
made of parallel fibrils which have diameter
of 50-90 nm.
The gap between two collagen molecules
is called Lacunar Zone.
7. introduction
Much thinner than collagen fibers with diameter of 0.5-2 m.μ
Made up of collagen protein (Type III fibrils)
It is visualized by Silver staining and PAS staining.
Also called Argyrophilic Fibers.
Present in Lymph Nodes, Spleen, Liver, Endocrine Glands, Bone Marrow,
Endomysium and Endoneurium
8. production
Bone Marrow and Lymph Nodes –
Reticular Cells
Liver, Spleen, Endocrine Glands –
Fibroblasts
Endoneurium – Schwann Cells
GIT and Arteries – Smooth Muscle
Cells