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Silicic acid (CAS 1343-98-2)

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Application:
Silicic acid is a silanol able to inhibit aluminum uptake
CAS Number:
1343-98-2
Molecular Weight:
78.11
Molecular Formula:
H2SiO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Silicic acid is a silanol found in the ocean, where its levels are regulated by diatoms. It may be useful for studying neurodegenerative diseases due to its ability to inhibit aluminum uptake.

References:

  1. Silicic acid: its gastrointestinal uptake and urinary excretion in man and effects on aluminium excretion.  |  Reffitt, DM., et al. 1999. J Inorg Biochem. 76: 141-7. PMID: 10612067
  2. The effect of different concentrations of silicic acid and silica dust on the biosynthesis of collagen in tissue cultures.  |  CHVAPIL, M. and HOLECKOVA, E. 1959. Br J Ind Med. 16: 286-9. PMID: 13810239
  3. A study of the alumina-silica gel adsorbent for the removal of silicic acid from geothermal water: increase in adsorption capacity of the adsorbent due to formation of amorphous aluminosilicate by adsorption of silicic acid.  |  Yokoyama, T., et al. 2002. J Colloid Interface Sci. 252: 1-5. PMID: 16290755
  4. Sorption of selenium(IV) onto magnetite in the presence of silicic acid.  |  Jordan, N., et al. 2009. J Colloid Interface Sci. 329: 17-23. PMID: 18947836
  5. Competition between selenium (IV) and silicic acid on the hematite surface.  |  Jordan, N., et al. 2009. Chemosphere. 75: 129-34. PMID: 19110295
  6. Glacial silicic acid concentrations in the Southern Ocean.  |  Ellwood, MJ., et al. 2010. Science. 330: 1088-91. PMID: 20966217
  7. Silicic acid in drinking water prevents age-related alterations in the endothelium-dependent vascular relaxation modulating eNOS and AQP1 expression in experimental mice: an immunohistochemical study.  |  Buffoli, B., et al. 2013. Acta Histochem. 115: 418-24. PMID: 23177919
  8. Silicic-acid uptake in diatoms studied with [(68)Ge]germanic acid as tracer.  |  Azam, F. 1974. Planta. 121: 205-12. PMID: 24442800
  9. The effect of silicic acid on calcium phosphate precipitation.  |  Damen, JJ. and ten Cate, JM. 1989. J Dent Res. 68: 1355-9. PMID: 2550533
  10. Interrelationship between hemolysis and lipid peroxidation of human erythrocytes induced by silicic acid and silicate dusts.  |  Singh, SV. and Rahman, Q. 1987. J Appl Toxicol. 7: 91-6. PMID: 3040843
  11. Silicic acid limitation drives bloom termination and potential carbon sequestration in an Arctic bloom.  |  Krause, JW., et al. 2019. Sci Rep. 9: 8149. PMID: 31148569
  12. Colloidal Dynamics of Freshly Formed Iron Oxides under the Influence of Silicic Acid.  |  Dam, TTN., et al. 2019. J Environ Qual. 48: 670-676. PMID: 31180432
  13. Structural Basis for Silicic Acid Uptake by Higher Plants.  |  van den Berg, B., et al. 2021. J Mol Biol. 433: 167226. PMID: 34487790
  14. Elevated ozone phytotoxicity ameliorations in mung bean {Vigna radiata (L.) Wilczek} by foliar nebulization of silicic acid and ascorbic acid.  |  Shahzadi, E., et al. 2022. Environ Sci Pollut Res Int. 29: 69680-69690. PMID: 35576036
  15. Computational modelling of diatom silicic acid transporters predicts a conserved fold with implications for their function and evolution.  |  Knight, MJ., et al. 2023. Biochim Biophys Acta Biomembr. 1865: 184056. PMID: 36191629