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Physiology of
deglutition
Dr. Roohia
2

Introduction
• Deglutition involves co-ordinated
activity of muscles of oral cavity,
pharynx, larynx and esophagus
• The whole process is partly under
voluntary control & partly
reflexive in nature
• Deglution by definition involves
passage of bolus of food (solid /
liquid) from the oral cavity to
stomach via the pharynx and
esophagus.
• Voluntary control of deglutition
involves control of jaw, tongue,
degree of constriction and length
of pharynx and closure of
laryngeal introitus
3

Components of deglutition
•
•
•
•

Deglution has 3 components
Passage of bolus from oral cavity to stomach
Protection of airway
Inhibition of air entry into the stomach
4

Deglutition - phases
• Oral
• Pharyngeal
• Esophageal
These stages have been traditionally described for
the sake of convenience. They help in the better
understanding of the physiological process
involved.
5

Oral phase
• In this phase food is prepared
for swallowing
 Tongue plays a vital role in this
process
• This phase is divided into oral
preparatory phase and oral
phase proper
• This phase is vital in all land
animals which don’t swallow
their food as a whole
• This phase is under voluntary
control
Oral preparatory phase
• This phase involves breaking down
of food in the oral cavity
• During this phase the food is
chewed and mixed with saliva
making it into a bolus which can be
swallowed
• The elevators of lower jaw play an
important role in bolus preparation
• Tongue plays a vital role in bolus
formation by the action of its
intrinsic muscles which alters its
shape. Its extrinsic muscles
changes its position within the oral
cavity thereby helping in chewing
the food by dental occlusion
• Occlusal action of the lips help in
creating an effective seal preventing
the bolus from dribbling out of the
oral cavity
• The action of buccinator muscle
helps in pushing the bolus out of the
vestibule into the oral cavity proper

6
7

oral preparatory phase (contd)
• SALIVARY GLANDS:
 Salivary glands connected to
mouth by ducts.
 Glands produce saliva.
 Saliva contains:
 Mucin- holds food together.
 Salivary amylase- starts
digesting carbohydrates.
 Bicarbonates-maintain PH
level of saliva&protect teeth.
 Lysozymes-inhibits
bact.,growth.
8

Bolus formation
• This is the most important
function of preparatory phase
• This involves repeated transfer
of food from oral cavity to
oropharyngeal surface of
tongue
• Bolus accumulates on the
oropharyngeal surface of
tongue due to repeated cycles
of upward & downward
movement of the tongue
Oral phase proper
• During this phase the bolus is moved
towards the back of the tongue
• The contraction of soft palate prevents
nasal regurgitation
• The soft palate also prevents
premature movement of bolus into the
oropharynx
• Once the bolus is of suitable
consistency the transit from mouth to
oropharynx just takes a couple of
seconds
• Tongue plays a vital role during this
phase. Its intrinsic muscles contracts
and reduces its size, while genioglossus
muscle elevates the tongue towards the
palate
• The elevation of the mandible plays a
vital role here
• When the mandible is elevated the
suprahyoid muscles raises the hyoid
bone

9
10

Pharyngeal phase (Pumping action of
tongue & hypopharyngeal suction)
• This phase of deglutition is reflexive in
nature
• It is during this phase that Ventilatory
and alimentary streams cross each other.
Dynamic separation of these streams is
possible due to the co-ordination of reflex
phase that occurs
• It just takes a second for the bolus to
traverse the pharynx and reach the
cricopharyngeal area
• Contraction of diaphragm is inhibited
making simultaneous breathing &
swallowing impossible
• Soft palate is elevated in order to seal off
the nasopharynx (T. palatini & L. palatini)
• Vocal cords adduct protecting the airway
• As the bolus passes the palatoglossal &
palatopharyngeal folds the act of
swallowing becomes reflexive
11

Functions of trigger points
in oropharynx
• Stimulation of trigger points present
in the oropharynx starts off the
pharyngeal reflexive stage of
swallowing
• Trigger points are present at the
faucial arches & mucosa of the
posterior pharyngeal wall
• These trigger points are innervated
by glossopharyngeal nerve
• Stimulation of these trigger points
causes dilatation of pharynx due to
relaxation of the constrictors, and
elevation of pharynx & larynx due to
contraction of longitudinal muscles
• The pharynx constricts behind the
bolus thereby propelling it
• Contraction of the inferior constrictor
moves the bolus towards the
oesophagus
12

Importance of laryngeal elevation
during pharyngeal stage
• It narrows the laryngeal inlet
• It ensures better sealing of the
laryngeal inlet by the downturned
epiglottis
• Laryngeal elevation also contributes
to dilatation of pharynx
• The laryngeal inlet is closed due to
the actions of interarytenoid,
aryepiglottic and thyroepiglottic
muscles
13

Role of epiglottis in the pharyngeal
phase
• The movement of epiglottis occurs
in two stages
• The epiglottis moves from vertical
– horizontal position
• The upper third of epiglottis moves
below the horizontal to a slightly
lower level to cover the narrowed
laryngeal inlet
• The bolus during the course of the
swallow impinges on the epiglottis
and gets diverted to the lateral food
channels
• Solid food tends to go behind the
epiglottis in to the post cricoid area
• Liquid food gets split by the
epiglottis and passes via the
pyriform fossae
14

Esophageal stage
• This is purely reflexive
• This phase begins by relaxing
the cricopharyngeal sphincter
• The time taken for esophageal
transit is 10-15 seconds
• Primary / secondary / tertiary
peristaltic waves play active
roles in this phase
15

Neural control of swallowing
• Two areas of brain are
involved
• Cerebral cortex
• Brain stem
16

Neural control (initiation)
• Initiation of swallow is voluntary
• Bilateral prefrontal, frontal and
parietal cortices are involved
• Swallowing is initiated when food
comes into contact with certain
trigger areas like fauces / mucosa
of posterior pharyngeal wall
• Afferent nerve is the
glossopharyngeal nerve
• Nucleus tractus solitarius &
spinal nucleus of trigeminal nerve
play a vital role
• Efferents involve several cranial
nerve nuclei which include
nucleus ambiguus (muscles of
palate, pharynx and larynx),
hypoglossal nucleus supplying the
muscles of the tongue, motor
nuclei of trigeminal and facial
nerves supplying the muscles of
face, jaws and lips.
17

Role of medulla
• There are two groups of neurons
in the medulla while lie between
the afferent and efferent system
• First group lie in the dorsal
medulla above the nucleus of
the solitary tract
• The second group lie in the
ventral medulla around nucleus
ambiguus
• These groups of neurons are
named as lateral & medial
medullary swallowing centers
18

Role of central pattern generator
• Central pattern generator
are a set of neurons capable
of initiating sequential
swallow
• These neurons act like a
cardiac pacemaker
• Since the process of
swallowing and breathing
are interlinked there is a
certain degree of central co
ordination taking place
19

Phase of respiration & swallowing
• Swallowing occurs during expiratory phase of
respiration
• This helps in clearing food material left in the
vestibule. Thus it should be considered to be a
protective phenomenon
• The rhythm of respiration is reset after a
successful swallow
20

STUDY OF SWALLOWING
21

INDICATIONS FOR STUDY OF
SWALLOWING
22

STUDY OF SWALLOWING
23

Fluroscopic imaging of swallowing
24
25
26
27
28
29
30
31
32

Double contrast image of pharynx
33

Examination of oesophagus
34

Dc image of gastro oesophageal
junction
35

Analysing disorders of swallowing
36

asymmetry
37

Stasis
38

Cricopharyngeal dysfunction
39
drtbalu's otolaryngology
online
40
drtbalu's otolaryngology
online
41
drtbalu's otolaryngology
online
42
drtbalu's otolaryngology
online
43
drtbalu's otolaryngology
online
44
drtbalu's otolaryngology
online
45

Aspiration
46

Web
47
48

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physiology of deglutition by ROOHIA

  • 2. 2 Introduction • Deglutition involves co-ordinated activity of muscles of oral cavity, pharynx, larynx and esophagus • The whole process is partly under voluntary control & partly reflexive in nature • Deglution by definition involves passage of bolus of food (solid / liquid) from the oral cavity to stomach via the pharynx and esophagus. • Voluntary control of deglutition involves control of jaw, tongue, degree of constriction and length of pharynx and closure of laryngeal introitus
  • 3. 3 Components of deglutition • • • • Deglution has 3 components Passage of bolus from oral cavity to stomach Protection of airway Inhibition of air entry into the stomach
  • 4. 4 Deglutition - phases • Oral • Pharyngeal • Esophageal These stages have been traditionally described for the sake of convenience. They help in the better understanding of the physiological process involved.
  • 5. 5 Oral phase • In this phase food is prepared for swallowing  Tongue plays a vital role in this process • This phase is divided into oral preparatory phase and oral phase proper • This phase is vital in all land animals which don’t swallow their food as a whole • This phase is under voluntary control
  • 6. Oral preparatory phase • This phase involves breaking down of food in the oral cavity • During this phase the food is chewed and mixed with saliva making it into a bolus which can be swallowed • The elevators of lower jaw play an important role in bolus preparation • Tongue plays a vital role in bolus formation by the action of its intrinsic muscles which alters its shape. Its extrinsic muscles changes its position within the oral cavity thereby helping in chewing the food by dental occlusion • Occlusal action of the lips help in creating an effective seal preventing the bolus from dribbling out of the oral cavity • The action of buccinator muscle helps in pushing the bolus out of the vestibule into the oral cavity proper 6
  • 7. 7 oral preparatory phase (contd) • SALIVARY GLANDS:  Salivary glands connected to mouth by ducts.  Glands produce saliva.  Saliva contains:  Mucin- holds food together.  Salivary amylase- starts digesting carbohydrates.  Bicarbonates-maintain PH level of saliva&protect teeth.  Lysozymes-inhibits bact.,growth.
  • 8. 8 Bolus formation • This is the most important function of preparatory phase • This involves repeated transfer of food from oral cavity to oropharyngeal surface of tongue • Bolus accumulates on the oropharyngeal surface of tongue due to repeated cycles of upward & downward movement of the tongue
  • 9. Oral phase proper • During this phase the bolus is moved towards the back of the tongue • The contraction of soft palate prevents nasal regurgitation • The soft palate also prevents premature movement of bolus into the oropharynx • Once the bolus is of suitable consistency the transit from mouth to oropharynx just takes a couple of seconds • Tongue plays a vital role during this phase. Its intrinsic muscles contracts and reduces its size, while genioglossus muscle elevates the tongue towards the palate • The elevation of the mandible plays a vital role here • When the mandible is elevated the suprahyoid muscles raises the hyoid bone 9
  • 10. 10 Pharyngeal phase (Pumping action of tongue & hypopharyngeal suction) • This phase of deglutition is reflexive in nature • It is during this phase that Ventilatory and alimentary streams cross each other. Dynamic separation of these streams is possible due to the co-ordination of reflex phase that occurs • It just takes a second for the bolus to traverse the pharynx and reach the cricopharyngeal area • Contraction of diaphragm is inhibited making simultaneous breathing & swallowing impossible • Soft palate is elevated in order to seal off the nasopharynx (T. palatini & L. palatini) • Vocal cords adduct protecting the airway • As the bolus passes the palatoglossal & palatopharyngeal folds the act of swallowing becomes reflexive
  • 11. 11 Functions of trigger points in oropharynx • Stimulation of trigger points present in the oropharynx starts off the pharyngeal reflexive stage of swallowing • Trigger points are present at the faucial arches & mucosa of the posterior pharyngeal wall • These trigger points are innervated by glossopharyngeal nerve • Stimulation of these trigger points causes dilatation of pharynx due to relaxation of the constrictors, and elevation of pharynx & larynx due to contraction of longitudinal muscles • The pharynx constricts behind the bolus thereby propelling it • Contraction of the inferior constrictor moves the bolus towards the oesophagus
  • 12. 12 Importance of laryngeal elevation during pharyngeal stage • It narrows the laryngeal inlet • It ensures better sealing of the laryngeal inlet by the downturned epiglottis • Laryngeal elevation also contributes to dilatation of pharynx • The laryngeal inlet is closed due to the actions of interarytenoid, aryepiglottic and thyroepiglottic muscles
  • 13. 13 Role of epiglottis in the pharyngeal phase • The movement of epiglottis occurs in two stages • The epiglottis moves from vertical – horizontal position • The upper third of epiglottis moves below the horizontal to a slightly lower level to cover the narrowed laryngeal inlet • The bolus during the course of the swallow impinges on the epiglottis and gets diverted to the lateral food channels • Solid food tends to go behind the epiglottis in to the post cricoid area • Liquid food gets split by the epiglottis and passes via the pyriform fossae
  • 14. 14 Esophageal stage • This is purely reflexive • This phase begins by relaxing the cricopharyngeal sphincter • The time taken for esophageal transit is 10-15 seconds • Primary / secondary / tertiary peristaltic waves play active roles in this phase
  • 15. 15 Neural control of swallowing • Two areas of brain are involved • Cerebral cortex • Brain stem
  • 16. 16 Neural control (initiation) • Initiation of swallow is voluntary • Bilateral prefrontal, frontal and parietal cortices are involved • Swallowing is initiated when food comes into contact with certain trigger areas like fauces / mucosa of posterior pharyngeal wall • Afferent nerve is the glossopharyngeal nerve • Nucleus tractus solitarius & spinal nucleus of trigeminal nerve play a vital role • Efferents involve several cranial nerve nuclei which include nucleus ambiguus (muscles of palate, pharynx and larynx), hypoglossal nucleus supplying the muscles of the tongue, motor nuclei of trigeminal and facial nerves supplying the muscles of face, jaws and lips.
  • 17. 17 Role of medulla • There are two groups of neurons in the medulla while lie between the afferent and efferent system • First group lie in the dorsal medulla above the nucleus of the solitary tract • The second group lie in the ventral medulla around nucleus ambiguus • These groups of neurons are named as lateral & medial medullary swallowing centers
  • 18. 18 Role of central pattern generator • Central pattern generator are a set of neurons capable of initiating sequential swallow • These neurons act like a cardiac pacemaker • Since the process of swallowing and breathing are interlinked there is a certain degree of central co ordination taking place
  • 19. 19 Phase of respiration & swallowing • Swallowing occurs during expiratory phase of respiration • This helps in clearing food material left in the vestibule. Thus it should be considered to be a protective phenomenon • The rhythm of respiration is reset after a successful swallow
  • 21. 21 INDICATIONS FOR STUDY OF SWALLOWING
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  • 34. 34 Dc image of gastro oesophageal junction
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